Causes of Gynecomastia aka ‘man boobs’

5avg.rating 52 votes.

The following medical conditions are some of the possible causes of Gynecomastia. There are likely to be other possible causes.

 

Klinefelter syndrome

Seminiferous tubule dysgenesis

Testicular failure

Androgen-insensitivity syndrome

Androgen receptor defects

Biosynthetic defects in testosterone production

Feminizing adrenocortical tumors

Isolated Leutenizing hormone deficiency

Testicular germ cell tumor

Leydig cell tumor

Sertoli cell tumor

Pseudogynecomastia

Obesity – may cause similar enlarged appearance.

Reifenstein syndrome

Kallmann syndrome

Liver cirrhosis

Puberty – all adolescent males experience some male breast enlargment; it is often temporary.

Drugs:

Antiandrogens (flutamide, finasteride, ketoconazole)

Gastrointestinal agents (cimetidine, ranitidine)

Digoxin

Calcium channel blockers (verapamil, nifedipine)

Marijuana

Heroin

Methadone

Amphetamines

Androgens

Anabolic steroids

Estrogens

Phenothiazines

Diazepam

Tricyclic antidepressants

Hyperthyroidism

Klinefelter’s syndrome

Isoniazid

Spirionolactone

Cimetidine

Omeprazole

Oestrogen

Methyldopa

Physiological

Testicular tumours

Adrenal carcinoma

Breast cancer

Hepatic carcinoma

Hypothyroidism

Pituitary tumor

Reifenstein’s syndrome

Testicular cancer

Hemodialysis

Major surgery

Testicular irradiation

Estrogens to treat prostate cancer

Ethylstilbestrol

Estramustine

Chlorotrianisene

Phenothiazine

Antihypertensives

Hepatoma

Hypogonadism

Aging – more common in older men as male hormones reduce.

Neurofibroma

Lung cancer

Dermoid cyst

Liver disorders

Lipoma

Liver disease

Estrogen-producing tumors

Certain tumors

Feminization

Chronic kidney failure

Adrenal tumor – if it secretes estrogen

Hematoma

Lymphamgioma

Ectopic hCG tumor

 

Tags: , , , ,